Major STIsTesting StrategyPrevention Planning

Sexual Health

This page presents structured information on major sexually transmitted infections (STIs), HIV prevention methods, and practical decision points for clinical follow-up.

Sexual health overview

Time-sensitive: If a potential HIV exposure occurred within 72 hours, request urgent clinical review for PEP.

Core prevention

Condom use, lubricant compatibility, routine testing, and informed partner communication.

Medical prevention

PrEP for planned prevention and PEP for emergency post-exposure intervention.

Escalation criteria

Severe symptoms, recent high-risk exposure, or sexual assault require urgent in-person care.

Disclaimer: Informational guidance only. This content does not diagnose conditions or provide medication instructions.

Major STI overview

Condition Typical concerns Testing and follow-up Prevention focus
HIV May be asymptomatic early; untreated infection progresses over time. Use recommended HIV testing windows and repeat as advised by clinician. Condoms, PrEP, PEP (within 72 hours), regular testing.
Syphilis Can present with painless sores or rash; may be missed without testing. Blood testing is central; repeat testing may be required after exposure. Barrier protection, partner notification, routine screening.
Gonorrhea May cause discharge, pain, or no symptoms. Site-specific testing may be needed based on exposure pattern. Condoms, regular screening, prompt treatment follow-up.
Chlamydia Frequently asymptomatic; can still transmit and cause complications. Laboratory screening based on exposure profile. Condom use and periodic screening.
Hepatitis B/C Liver-related infection risk depending on exposure type. Blood-based testing when indicated by clinician. Vaccination (where applicable), safer sex, clinical monitoring.
HPV Common viral infection; some strains linked to long-term disease risk. Assessment depends on symptoms and clinician judgment. Vaccination eligibility discussion and safer practices.
Herpes (HSV) Recurrent painful lesions in some cases; asymptomatic shedding can occur. Clinical assessment during symptomatic episodes is useful. Barrier protection and informed disclosure with partners.
HIV prevention planning: PrEP vs PEP

PrEP is a proactive prevention strategy for ongoing risk profiles. PEP is an emergency response started as soon as possible after exposure and within a limited time window.[4][5]

Testing cadence and retesting

One negative result may not close all risk windows. Use clinician-led timing and repeat testing where indicated.[3]

When to seek urgent in-person care

Severe genital symptoms, fever with recent risk exposure, potential HIV exposure within 72 hours, or assault concerns require rapid clinical review.

Professional communication template

“I need a confidential STI/HIV risk assessment based on recent exposure, with clear guidance on what to test now and what to retest later.”

Sources

[1] WHO HIV fact sheet – https://www.who.int/news-room/fact-sheets/detail/hiv-aids

[2] WHO STI fact sheet – https://www.who.int/news-room/fact-sheets/detail/sexually-transmitted-infections-(stis)

[3] CDC HIV testing – https://www.cdc.gov/hiv/testing/index.html

[4] CDC PrEP – https://www.cdc.gov/hiv/prevention/prep.html

[5] CDC PEP – https://www.cdc.gov/hiv/prevention/pep.html